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Biomedical Engineering Laboratory is focused at searching (and finding) practical solutions in the field of medicine and pharmacy: innovative drug release systems, less invasive medical devices and regenerative medicine.

Research topics:

• medical coatings: athrombogenic, antibacterial, hydrogel, etc.
• nanosystems for anticancer therapy
• bone implants
• 3D printing

Infrastructure:

• confocal microscope  LSM 880 (Zeiss)
• microscope Eclipse 80i (Nikon)
• electron microskope Phenom (Phenom World)
• spektrometer FT-IR Nicolet 6700 (Thermo Scientific)
• goniometer DSA 100 (Kruss) 
• coagulometer CA 660 (Siemens)
• microplate reader Epoch (BioTek)
• clean room
• nanoparticles analyzer NanoSight

Selected papers:

• Kośnik W., Sikorska H., Kiciak A., Ciach T.: Nanoparticle-Encapsulated Epirubicin Efficacy in the Inhibition of Growth of Orthotopic Ovarian Patient-Derived Xenograft in Immunocompromised Mice, International Journal of Molecular Sciences, MDPI, vol. 25, no. 1, 2024, Article number: 645, pp. 1-17, DOI:10.3390/ijms25010645, IF(6.208)
• Asendrych-Wicik K., Zarczuk J., Walaszek K., Ciach T., Markowicz-Piasecka M.: Trends in development and quality assessment of pharmaceutical formulations - F2α analogues in the glaucoma treatment, European Journal of Pharmaceutical Sciences, Elsevier BV, vol. 180, 2023, Article number: 106315, pp. 1-26, DOI:10.1016/j.ejps.2022.106315, IF(4.384)
• Baran J., Kuryk Ł., Szczepińska  T., Łaźniewski M., Mazurkiewicz-Pisarek A., Trzaskowski  M., Plewczyński D., Ciach T., Mierzejewska J., Staniszewska M.: In vitro immune evaluation of adenoviral vector-based platform for infectious diseases, BioTechnologia Journal of Biotechnology, Computational Biology and Bionanotechnology, Ośrodek Wydawnictw Naukowych OWN, vol. 104, no. 4, 2023, pp. 403-419, DOI:10.5114/bta.2023.132775
• Kopeć K., Podgórski R., Ciach T., Wojasiński M.: System for Patterning Polydopamine and VAPG Peptide on Polytetrafluoroethylene and Biodegradable Polyesters for Patterned Growth of Smooth Muscle Cells In Vitro, ACS Omega, ACS Publications, vol. 8, no. 24, 2023, pp. 22055-22066, DOI:10.1021/acsomega.3c02114, IF(3.512)
• Kowalczyk P., Kopeć K., Wojasiński M., Jaroszewicz J., Ciach T.: Composite microgranular scaffolds with surface modifications for improved initial osteoblastic cell proliferation, Biomaterials Advances, Elsevier B.V., vol. 151, 2023, Article number: 213489, DOI:10.1016/j.bioadv.2023.213489
• Kowalczyk P., Wojasiński M., Jaroszewicz J., Kopeć K., Ciach T.: Controlled formation of highly porous polylactic acid‑calcium phosphate granules with defined structure, Biomaterials Advances, Elsevier B.V., vol. 144, 2023, Article number: 213195, pp. 1-16, DOI:10.1016/j.bioadv.2022.213195
• Mazurkiewicz-Pisarek A., Baran J., Ciach T.: Antimicrobial Peptides: Challenging Journey to the Pharmaceutical, Biomedical, and Cosmeceutical Use, International Journal of Molecular Sciences, MDPI, vol. 24, no. 10, 2023, Article number: 9031, pp. 1-32, DOI:10.3390/ijms24109031, IF(6.208)
• Mazurkiewicz-Pisarek A., Mazurkiewicz A., Mikiewicz D., Baran P., Ciach T.: Expression of the gene encoding blood coagulation factor VIII without domain B in E. coli bacterial expression system, BioTechnologia Journal of Biotechnology, Computational Biology and Bionanotechnology, Ośrodek Wydawnictw Naukowych OWN, vol. 104, no. 3, 2023, pp. 247-262, DOI:10.5114/bta.2023.130728
• Młynek M., Trzciński J., Ciach T.: Recent Advances in the Polish Research on Polysaccharide-Based Nanoparticles in the Context of Various Administration Routes, Biomedicines, vol. 11, no. 5, 2023, Article number: 1307, pp. 1-22, DOI:10.3390/biomedicines11051307
• Pachla J., Kopiasz R., Marek G., Tomaszewski W., Drężek K., Kowalczyk S., Podgórski R., Butruk-Raszeja B., Ciach T., Mierzejewska J.: Polytrimethylenimines: Highly Potent Antibacterial Agents with Activity and Toxicity Modulated by the Polymer Molecular Weight, Biomacromolecules, vol. 24, no. 5, 2023, pp. 2237-2249, DOI:10.1021/acs.biomac.3c00139, IF(6.988)